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Search Results for Division/School: Department of Biochemistry
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(Thesis, Master of Science, 2012)Gout and cardiovascular disease are both complex and multi-factorial with genetic predisposition and environmental triggers. Not only do both have high co-morbidity with other metabolic conditions, gout patients have high ... -
(Thesis, Master of Science, 2010)In forensic investigations the distinction between expirated bloodstains (blood from the mouth, nose or lungs) and impact spatter (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) is often ... -
(Thesis, Master of Science, 2010)The PsbT subunit of photosystem II (PSII) is a single α-helical trans-membrane protein found at the monomer-monomer interface of PSII dimers. During oxygen evolution by PSII in the cyanobacterium Synechocystis sp. PCC 6803, ... -
(Thesis, Master of Science, 2011)This thesis looks at the role of bone morphogenetic proteins (BMPs) during tail development in Xenopus laevis. BMPs are a group of signalling molecules and their role was studied by inhibiting them from the onset of ... -
(Thesis, Master of Science, 2011)Hydrogenases for the production of hydrogen are found in many microorganisms. The isolation of a stable hydrogenase enzyme would be beneficial for the development of an in vitro system for hydrogen production as a fuel. ... -
(Thesis, Master of Science, 2011)Gout is a common disease caused by immune response to monosodium urate (MSU) crystal deposition in articular or periarticular tissues and in the renal tract after chronic hyperuricemia (uric acid levels exceeding 7mg/dL). ... -
(Thesis, Doctor of Science, 2010)Transfer RNA (tRNA) is an ancient molecule with a myriad of functions in modern biology; however, its pre-eminent role is in the transfer of individual amino acids to the growing polypeptide chain in protein synthesis. The ... -
(Thesis, Master of Science, 2010)The adiponutrin gene (Adpn) and its human homologue PNPLA3 code for a protein which is highly expressed in adipose tissue and liver, and appears to be involved in regulation of energy homeostasis. The nutritional regulation ... -
(Thesis, Master of Health Sciences, 2010)Streptococcus salivarius, a predominant bacterial species found in the human oral cavity, is increasingly studied for its production of bacteriocin-like activity. Much of the interest in the study of S. salivarius is driven ... -
Is release factor 2 uniquely regulated because it is a key transcriptional regulator of other genes? (Thesis, Master of Science, 2011)Prokaryotes contain two release factors, RF1 and RF2, both decode the UAA stop codon but individually they are specific for UAG and UGA respectively. The prfB gene, encoding RF2, uniquely has a sophisticated autoregulation ...