Otago University Research Archive
Browsing Department of Biochemistry by Title
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Browsing Department of Biochemistry by Title
Now showing items 1-20 of 64
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(Thesis, Master of Science, 2011)Nearly 3% of the world ’s population is affected by some form of autoimmune disease, with current estimates of rheumatoid arthritis (RA) prevalence at 0.7-1% of Caucasians. This degenerative disorder is characterized by ... -
(Thesis, Doctor of Philosophy, 2010)Homing endonucleases are highly specific DNases, commonly called HEGs, encoded by self-splicing intein and intron sequences. They recognise long target sequences and confer mobility to their host sequence by introducing a ...
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(Thesis, Doctor of Philosophy, 2012)Inteins are naturally-occurring intervening sequences that are translated along with their host protein. The intein insertion is excised from its host protein post-translationally in an autocatalytic process known as intein ...
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(Thesis, Doctor of Philosophy, 2007)Facial eczema disease (FE) is a secondary photosensitisation disease of ruminants caused by exposure to the mycotoxin sporidesmin. Resistance to FE has a significant genetic component and previous research has included a ...
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(Thesis, Master of Science, 2010)DnaK is a 70 kilodalton heat shock protein and molecular chaperone from Escherichia coli with an N-terminal nucleotide binding domain and C-terminal substrate binding domain. During chaperone function DnaK occupies at least ... -
(Thesis, Doctor of Philosophy, 2011)Sea urchin roe is a highly valued product in the international marketplace. New Zealand’s coastal zones, have significant stocks of sea urchin (Evechinus chloroticus; local name Kina), but quality issues including colour, ...
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(Thesis, Doctor of Philosophy, 2012)The dicot model plant Arabidopsis thaliana (A. thaliana) contains four copies of the sucrose phosphate synthase (SPS) gene. In this project, the quantitative real-time PCR (qPCR) technique was validated to investigate the ...
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(Thesis, Master of Science, 2010)Amphibian species have been experiencing a massive global decline during the past few decades. Chytridiomycosis, caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd), is a cutaneous infectious disease that leads ...
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(Thesis, Master of Science, 2010)The PsbT subunit of photosystem II (PSII) is a single α-helical trans-membrane protein found at the monomer-monomer interface of PSII dimers. During oxygen evolution by PSII in the cyanobacterium Synechocystis sp. PCC 6803, ... -
(Thesis, Master of Science, 2011)The Cfm2 gene is conserved in vertebrates and is linked to various developmental anomalies in humans. This gene is a paralogue of another novel gene named Cfm, for caudal forebrain and midbrain. In the mouse, Cfm was found ... -
(Thesis, Doctor of Philosophy, 2012)Cardiovascular disease (CVD) is a leading cause of premature death in New Zealand and in the developed world. Numerous epidemiological studies have identified elevated plasma levels (>500 mg/l) of the cholesterol-rich ...
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(Thesis, Doctor of Philosophy, 2004)The autoimmune diseases embody a diverse range of common human conditions that are caused by a loss of self-tolerance in the host immune system to a specific organ or tissue type. Approximately 5% of the general population ...
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(Thesis, Master of Science, 2012)The instrument I constructed in this project was a bare platinum electrode based on the original electrode by Pierre Joliot (Joliot P. (1972). Methods in Enzymology 24, 123–124) and the design by Johannes Messinger (Messinger ...
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(Thesis, Doctor of Philosophy, 2013)In cell-surface signalling pathways, the binding of an iron chelate to a specific outer membrane receptor induces gene expression in the cytoplasm via extra-cytoplasmic function sigma proteins. In these pathways gene ...
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(Thesis, Doctor of Philosophy, 2011)Folic acid and natural folates are B group vitamins obtained exclusively from the diet. Biochemically, folate derivatives participate in the transfer of single carbon units, acting as methyl group donors for numerous ... -
(Thesis, Doctor of Philosophy, 2010)In vitro fertilisation (IVF) potentially provides a profoundly abnormal environment for an embryo. Studies with mice, sheep and cattle have indicated that the culture environment of the embryo can affect the imprinting of ... -
(Thesis, Master of Science, 2011)Hydrogenases for the production of hydrogen are found in many microorganisms. The isolation of a stable hydrogenase enzyme would be beneficial for the development of an in vitro system for hydrogen production as a fuel. ... -
(Thesis, Doctor of Philosophy, 2012)Honeybees are incredible organisms. They produce two morphologically, and behaviourally distinct adult forms from a single genome; a remarkable example of developmental plasticity. The diet a female honeybee larva receives ...
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(Thesis, Master of Science, 2011)Forebrain embryonic zinc-finger family member 2 (FEZF2) is a transcription factor that is expressed at high levels in corticospinal motor neurons and related subcerebral projection neurons from early in development through ...
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(Thesis, Master of Science, 2010)In forensic investigations the distinction between expirated bloodstains (blood from the mouth, nose or lungs) and impact spatter (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) is often ...
Now showing items 1-20 of 64