Otago University Research Archive
Browsing Department of Biochemistry by Date Published
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Browsing Department of Biochemistry by Date Published
Now showing items 1-20 of 65
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(Thesis, Master of Science, 2013)The objective of this research was to determine whether the Type IV pili of Synechocystis sp. PCC 6803 are involved in electron donation to the extracellular environment. In conjunction with the current theories and published ...
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(Thesis, Master of Science, 2013)Honeybees (Apis mellifera) are remarkable creatures with a complex eusocial hive structure. There are two female honeybee castes within a hive; a single queen and thousands of workers. The only reproductively active female ... -
(Thesis, Doctor of Philosophy, 2013)In cell-surface signalling pathways, the binding of an iron chelate to a specific outer membrane receptor induces gene expression in the cytoplasm via extra-cytoplasmic function sigma proteins. In these pathways gene ...
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(Thesis, Doctor of Philosophy, 2013)Colorectal cancer (CRC) is proposed to originate through three major molecular pathways, chromosomal instability (CIN), microsatellite instability (MSI) and the CpG island methylator phenotype (CIMP). Many studies have ...
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(Thesis, Doctor of Philosophy, 2013)Photosystem II is a large protein complex that catalyses the light-driven oxidation of water. The biogenesis of Photosystem II is a regulated process that involves transient interactions between Photosystem II and dedicated ...
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(Thesis, Master of Science, 2012)During a cyanobacterial bloom in Lake Omapere, cyanobacterial toxins were detected in Crassostrea gigas (Pacific oyster) from the Hokianga Harbour using Enzyme-Linked immunosorbent assay (ELISA). However, Detection and ...
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(Thesis, Doctor of Philosophy, 2012)The process of human decomposition in marine environments, particularly that of partial human remains, is a significantly understudied area of forensic taphonomic research. Since partial remains lack the enteric microflora ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Lipoprotein(a) [Lp(a)] is a plasma lipoprotein, characterised by an apo(a) molecule bound via a disulphide bond to apoB of a low density lipoprotein- (LDL-) like particle. Elevated Lp(a) levels are a well established risk ...
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(Thesis, Doctor of Philosophy, 2012)Honeybees are incredible organisms. They produce two morphologically, and behaviourally distinct adult forms from a single genome; a remarkable example of developmental plasticity. The diet a female honeybee larva receives ...
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(Thesis, Doctor of Philosophy, 2012)Inteins are naturally-occurring intervening sequences that are translated along with their host protein. The intein insertion is excised from its host protein post-translationally in an autocatalytic process known as intein ...
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(Thesis, Master of Science, 2012)The PAX gene family encodes a group of transcription factors that play important roles during embryogenesis with mutations resulting in developmental abnormalities. Normally expression of these genes is downregulated prior ... -
(Thesis, Doctor of Philosophy, 2012)One of the major problems facing the world in the 21st century is feeding a growing population on ever-decreasing arable land. The majority of the world’s calorific intake comes from seeds, primarily those of wheat, rice ... -
(Thesis, Master of Science, 2012)How developmental pathways evolve to produce different morphologies is an exciting area of study. Most knowledge of invertebrate development is from D. melanogaster, or other holometabolous insects. However, the more ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germline mutations in the CDH1 gene which encodes the calcium-dependent, cell-cell adhesion protein E-cadherin [1,2]. Early stage ... -
(Thesis, Doctor of Philosophy, 2012)The life history trade off between longevity and reproduction is seen in a variety of animals. In the model organism Drosophila melanogaster, regulation of lifespan and reproductive rate are linked to various ratios of ...
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(Thesis, Master of Science, 2012)The formation of the ovarian follicles and the subsequent recruitment to proceed to ovulation is a complex mechanism involving both local and external signals. Early hormonal unresponsive follicles develop to a mature ...
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(Thesis, Doctor of Philosophy, 2012)Cardiovascular disease (CVD) is a leading cause of premature death in New Zealand and in the developed world. Numerous epidemiological studies have identified elevated plasma levels (>500 mg/l) of the cholesterol-rich ...
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(Thesis, Master of Science, 2012)Alzheimer’s disease is characterised by progressive loss of memory and cognitive functions. The symptoms extend to severe dementia and, in extreme cases, death. The neurological damage arises from the accumulation of a ... -
(Thesis, Master of Science, 2012)Gout and cardiovascular disease are both complex and multi-factorial with genetic predisposition and environmental triggers. Not only do both have high co-morbidity with other metabolic conditions, gout patients have high ... -
(Thesis, Doctor of Philosophy, 2012)Low levels of high-density lipoprotein cholesterol (HDL-C) are an independent risk factor for the development of cardiovascular disease (CVD). The ATP-binding cassette transporter A1 (ABCA1) is a major genetic determinant ...
Now showing items 1-20 of 65