Otago University Research Archive
Browsing Department of Biochemistry by Date Added
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Browsing Department of Biochemistry by Date Added
Now showing items 1-20 of 63
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(Thesis, Doctor of Philosophy, 1972)Bacteriophage T5 possesses a double-stranded DNA molecule containing single-strand interruptions and, as a result, denatured T5 DNA consists of a number of single-stranded DNA fragments. The objectives of this investigation ...
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(Thesis, Doctor of Philosophy, 2009)Elevated low density lipoprotein (LDL) and lipoprotein(a) (Lp(a)) levels are independent risk factors for the development of cardiovascular disease. Lp(a) transgenic mice can be generated by cross-breeding human apolipoprotein ...
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(Thesis, Doctor of Philosophy, 2013)In cell-surface signalling pathways, the binding of an iron chelate to a specific outer membrane receptor induces gene expression in the cytoplasm via extra-cytoplasmic function sigma proteins. In these pathways gene ...
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(Thesis, Master of Science, 2010)Amphibian species have been experiencing a massive global decline during the past few decades. Chytridiomycosis, caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd), is a cutaneous infectious disease that leads ...
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(Thesis, Doctor of Philosophy, 2007)Facial eczema disease (FE) is a secondary photosensitisation disease of ruminants caused by exposure to the mycotoxin sporidesmin. Resistance to FE has a significant genetic component and previous research has included a ...
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(Thesis, Master of Science, 2013)Honeybees (Apis mellifera) are remarkable creatures with a complex eusocial hive structure. There are two female honeybee castes within a hive; a single queen and thousands of workers. The only reproductively active female ... -
(Thesis, Master of Science, 2013)The objective of this research was to determine whether the Type IV pili of Synechocystis sp. PCC 6803 are involved in electron donation to the extracellular environment. In conjunction with the current theories and published ...
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(Thesis, Doctor of Philosophy, 2013)Colorectal cancer (CRC) is proposed to originate through three major molecular pathways, chromosomal instability (CIN), microsatellite instability (MSI) and the CpG island methylator phenotype (CIMP). Many studies have ...
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(Thesis, Doctor of Philosophy, 2004)The autoimmune diseases embody a diverse range of common human conditions that are caused by a loss of self-tolerance in the host immune system to a specific organ or tissue type. Approximately 5% of the general population ...
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(Thesis, Doctor of Philosophy, 2003)
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(Thesis, Doctor of Philosophy, 2007)The human hepatitis B virus (HBV) is a small hepatotropic virus, which affects approximately 350 million chronic sufferers worldwide. It has a compact 3.2 kbp dsDNA genome encoding four major overlapping genes namely core, ...
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(Thesis, Doctor of Philosophy, 2010)Homing endonucleases are highly specific DNases, commonly called HEGs, encoded by self-splicing intein and intron sequences. They recognise long target sequences and confer mobility to their host sequence by introducing a ...
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(Thesis, Master of Science, 2012)The instrument I constructed in this project was a bare platinum electrode based on the original electrode by Pierre Joliot (Joliot P. (1972). Methods in Enzymology 24, 123–124) and the design by Johannes Messinger (Messinger ...
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(Thesis, Doctor of Philosophy, 2012)The dicot model plant Arabidopsis thaliana (A. thaliana) contains four copies of the sucrose phosphate synthase (SPS) gene. In this project, the quantitative real-time PCR (qPCR) technique was validated to investigate the ...
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Structure and function of the extrinsic lipoproteins of Photosystem II in Synechocystis sp. PCC 6803 (Thesis, Doctor of Philosophy, 2012)The cyanobacterium Synechocystis sp. PCC6803 contains six extrinsic Photosystem II proteins located in the thylakoid lumen. Three of these, CyanoP, CyanoQ and Psb27 (homologues of the higher plant PsbP, PsbQ and Psb27 ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Lipoprotein(a) [Lp(a)] is a plasma lipoprotein, characterised by an apo(a) molecule bound via a disulphide bond to apoB of a low density lipoprotein- (LDL-) like particle. Elevated Lp(a) levels are a well established risk ...
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(Thesis, Master of Science, 2012)During a cyanobacterial bloom in Lake Omapere, cyanobacterial toxins were detected in Crassostrea gigas (Pacific oyster) from the Hokianga Harbour using Enzyme-Linked immunosorbent assay (ELISA). However, Detection and ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germline mutations in the CDH1 gene which encodes the calcium-dependent, cell-cell adhesion protein E-cadherin [1,2]. Early stage ... -
(Thesis, Master of Science, 2012)How developmental pathways evolve to produce different morphologies is an exciting area of study. Most knowledge of invertebrate development is from D. melanogaster, or other holometabolous insects. However, the more ...
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(Thesis, Doctor of Philosophy, 2012)One of the major problems facing the world in the 21st century is feeding a growing population on ever-decreasing arable land. The majority of the world’s calorific intake comes from seeds, primarily those of wheat, rice ...
Now showing items 1-20 of 63