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Browsing Physiology by Title
Now showing items 1-20 of 29
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(Thesis, Doctor of Philosophy, 2010)Altered reinforcement sensitivity is an important characteristic of Attention Deficit Hyperactivity Disorder (ADHD). In order to elucidate the neurobiological mechanisms behind this characteristic, an appropriate animal ... -
(Thesis, Doctor of Philosophy, 2011)Epilepsy affects around 1 % of the population, and up to a third of patients are resistant to antiepileptic drugs (AEDs). Epilepsy is defined as an enduring predisposition of the brain to generate seizures, and the disorder ...
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(Thesis, Doctor of Philosophy, 1997)
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(Thesis, Doctor of Philosophy, 2010)B-lymphocytes have been implicated as key mediators of inflammation and autoimmune disease. However, the mechanisms involved have yet to be fully elucidated. What is known is summarised in Chapter 1. The overall aim of the ...
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Cardiac function and β-adrenergic receptor responsiveness in the isolated human diabetic myocardium (Thesis, Bachelor of Biomedical Sciences with Honours, 2012)The prevalence of type 2 diabetic mellitus is closely associated with cardiovascular complications. Diabetic patients with preserved ejection fraction (EF) are at high risk of developing heart failure. Until now, little ...
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(Thesis, Bachelor of Medical Science with Honours, 2011)The hormone oxytocin is secreted from nerve terminals of oxytocin magnocellular cells (MNCs) in the posterior pituitary gland and is important in the timing of birth and is essential for milk secretion. Another reproductive ... -
(Thesis, Doctor of Philosophy, 2011)The cerebellum has often been referred to as the "neuronal machine", so called for the elegant architecture of neuronal circuitry and necessarily clockwork precision of signal transmission therein (Eccles 1967; Ito 2006). ...
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(Thesis, Doctor of Philosophy, 2012)Abstract The primary aim of this thesis was to describe the dynamic response characteristics of leg blood flow (LBF) and leg vascular conductance (LVC) during exercise and recovery, and to investigate the influence of ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2011)Abstract Increased cardiac sympathetic drive as a consequence of increased renal sympathetic activity is an important contributor to the development of cardiovascular complications in patients with diabetic nephropathy. ...
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(Thesis, Doctor of Philosophy, 2011)The extent to which systemic hypoxia may compromise cerebrovascular function is likely to depend on the intensity and duration of the hypoxic insult. This thesis presents four studies that used a range of intermittent and ...
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(Thesis, Doctor of Philosophy, 2011)The maintenance of adequate cerebral blood flow (CBF) is important both acutely and chronically, is highly dependent on mean arterial pressure (MAP) and the partial pressure of arterial carbon dioxide (PaCO2), and can be ... -
(Thesis, Doctor of Philosophy, 2012)The gonadotropin-releasing hormone (GnRH) neurons, located within the hypothalamus of the mammalian brain, have been established as the key output cells mediating all influences that control fertility, conveyed by the ...
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(Thesis, Doctor of Philosophy, 2011)Spinal cord injury (SCI) is a debilitating disorder, causing cardiovascular dysfunction at rest and during orthostasis [as simulated by lower-body negative pressure (LBNP)], which differs with the level, completeness, and ...
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(Thesis, Master of Science, 2012)The neuronal voltage gated Ca2+ channel CaV2.1, regulates neurotransmitter release. Recently, the E1015K polymorphism was identified in the SNARE interaction synprint site of CaV2.1 in migraine patients. In this study, we ...
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(Thesis, Doctor of Philosophy, 2012)In the intestine of eutherian mammals, such as human, rabbit, rat and mouse, fluid secretion is primarily driven by Cl- transport. However, in the ileum of possum (Trichosurus vulpecula), a metatherian mammal, the fluid ...
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(Thesis, Doctor of Philosophy, 2012)Gonadotropin-releasing hormone (GnRH) neurons are the final output neurons of a hypothalamic network controlling fertility in mammals. They release GnRH from axon terminals into the portal blood circulation of the pituitary, ...
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(Thesis, Doctor of Philosophy, 2011)The epithelial sodium channel (ENaC) is located at the apical membrane of many epithelial cells throughout the body and mediates Na+ influx into epithelial cells. Classical ENaC is made up of three similar subunits, α, β ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Polycystic ovarian syndrome (PCOS) is the most common cause of infertility among women of reproductive age worldwide. Although the aetiology is unclear, there are a number of neuroendocrine disruptions which identify PCOS ... -
(Thesis, Master of Science, 2010)The amiloride-sensitive epithelial sodium channel (ENaC), which is a key regulator of sodium (Na+) homeostasis, is expressed as a protein complex on the apical cell surface of many epithelial cells. ENaC is composed of ... -
(Thesis, Doctor of Philosophy, 2011)For over fifty years the elemental cation lithium (Li⁺) has been the primary agent used in the treatment and prophylaxis of bipolar disorder, but its therapeutic mechanism of action remains unknown. Bipolar disorder is ...
Now showing items 1-20 of 29