Otago University Research Archive
Browsing Microbiology and Immunology by Date Published
Otago University Research Archive
- OUR Archive Home
- →
- Division of Health Sciences Departments
- →
- Otago School of Medical Sciences
- →
- Microbiology and Immunology
- →
- Browsing Microbiology and Immunology by Date Published
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Microbiology and Immunology by Date Published
Now showing items 1-20 of 53
-
(Thesis, Doctor of Philosophy, 2013)The immune system has the potential to detect and destroy tumour cells, however naturally occurring anti-tumour immunity is not always capable of controlling tumour growth. Immunotherapy can harness the anti-tumour function ...
-
(Thesis, Master of Science, 2013)Most streptococcal species are essentially non-pathogenic and are part of the normal commensal microflora of the mouth, skin, intestine, and upper respiratory tract of humans (and other animals). Streptococcus salivarius ... -
(Thesis, Doctor of Philosophy, 2013)Members of the genus Mycobacterium are able to degrade cholesterol and for pathogenic members like Mycobacterium tuberculosis this degradation has been implicated in persistence in the lungs of the chronically infected ...
-
(Thesis, Doctor of Philosophy, 2013)Infectious disease accounts for the highest percentage of preventable deaths worldwide and today’s health care systems are predominately reliant upon antibiotics to treat bacterial infections bacterial strains. Serious ... -
(Thesis, Doctor of Philosophy, 2012)Human noroviruses are highly infectious viruses that cause the majority of acute, non-bacterial epidemic gastroenteritis cases worldwide. Noroviruses belong to the family Caliciviridae and have a positive-sense RNA genome ...
-
(Thesis, Master of Science, 2012)Immunotherapies prime cells of the immune system to generate an appropriate response against a specific target. One area of Immunotherapeutic research is the development of cancer vaccines such as the vaccines based on ... -
(Thesis, Doctor of Philosophy, 2012)The poxviruses are an extensive family of large DNA viruses, including the causative agent for smallpox, variola virus. The success of poxviruses as pathogens is in part due to their expression of an array of gene products ...
-
(Thesis, Doctor of Philosophy, 2012)Resistance and susceptibility to infectious diseases are well-documented in a variety of host species. While environmental modifiers and pathogen virulence influence disease severity following infection, a major contributor ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Primary tumours are rarely lethal; instead most cancer deaths are due to the spreading of the tumour to other sites in the body (metastasis). One major pathway of metastatic disease is the migration of tumour cells from ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2012)Virus-like particles (VLP) have been shown to be effective vessels for drug or gene delivery, and vaccination. Much research has focused on the generation of VLP carrying heterologous tumour antigens to initiate cell-mediated ... -
(Thesis, Master of Science, 2012)A strain of Micrococcus luteus, isolated from the epidermis of an adult human male, produces anti-bacterial activity in vitro. The purpose of this study was to investigate the potential value of this bacterium, designated ...
-
(Thesis, Doctor of Philosophy, 2012)Serratia sp. ATCC 39006 (Serratia 39006) is a Gram-negative bacterium from the Enterobacteriaceae family. Serratia 39006 is able to produce a number of secondary metabolites including the red tripyrrole antibiotic prodigiosin ...
-
(Thesis, Doctor of Philosophy, 2012)The establishment of a successful symbiotic interaction between rhizobia and legumes requires complex molecular communication between the two partners in order to determine compatibility and co-ordinate symbiotic developmental ... -
(Thesis, Master of Science, 2012)Bacteria live in environments where they are constantly under attack by bacteriophage (phage) and are subjected to horizontal gene transfer (HGT) events, such as transfer of plasmids. Bacteria have developed many systems ...
-
(Thesis, Master of Science, 2012)One contentious method by which bacteria deal with a maladapted situation is what has been coined ‘adaptive’, ‘directed’ or ‘stress induced-mutation’. This involves mutants that compensate for some form of sub-lethal stress ... -
(Thesis, Master of Science, 2012)Johne’s disease (JD), caused by the pathogen Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic inflammatory bowel disease of ruminants that is characterised in its clinical stage by progressive weight ... -
(Thesis, Doctor of Philosophy, 2011)The primary risk factor for the development of cervical cancer is a persistent infection with certain high-risk human papillomavirus (HPV) types such as 16 and 18. The ability of these viruses to cause such persistent ...
-
(Thesis, Doctor of Philosophy, 2011)The genome of Mycobacterium smegmatis contains three putative toxin-antitoxin (TA) systems. The vapBC system has been characterized, but the remaining two TA systems, belonging to the mazEF and phd/doc family have not been ...
-
(Thesis, Doctor of Philosophy, 2011)Virus-like particles (VLP) have been shown to be useful nanoscale platforms in a diverse range of applications including their use as vaccines. They can act as vehicles for the delivery of heterologous antigens to the ...
-
(Thesis, Master of Science, 2011)Bacterial vaginosis (BV) is one of the infections that predispose pregnant women to preterm labour and post delivery complications. The use of antibiotics to treat the BV is not effective with high recurrent cases and ...
Now showing items 1-20 of 53